Metixene hydrochloride hydrate

CAS No. 7081-40-5

Metixene hydrochloride hydrate( —— )

Catalog No. M37950 CAS No. 7081-40-5

Metixene hydrochloride hydrate has potential anticholinergic activity and inhibits the binding of quinine ring benzoate (QNB) to muscarine receptors, with IC50 and Ki values of 55 nM and 15 nM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 33 In Stock
10MG 52 In Stock
25MG 104 In Stock
50MG 164 In Stock
100MG 260 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Metixene hydrochloride hydrate
  • Note
    Research use only, not for human use.
  • Brief Description
    Metixene hydrochloride hydrate has potential anticholinergic activity and inhibits the binding of quinine ring benzoate (QNB) to muscarine receptors, with IC50 and Ki values of 55 nM and 15 nM, respectively.
  • Description
    Metixene (Piperidine) hydrochloride hydrate is an anticholinergic and antiparkinsonian agent. Metixene hydrochloride hydrate potently inhibits binding of quinuclidinyl benzilate (QNB) with the muscarinic receptor, IC50 and Ki values of 55 nM and 15 nM, respectively. Metixene hydrochloride hydrate can be used for the research of parkinsonian.
  • In Vitro
    Metixene hydrochloride hydrate can potentially inhibit the binding of QNB with the muscarinic receptor, IC50 and Ki values of 55 nM and 15 nM, respectively.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    AChR
  • Recptor
    AChR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    7081-40-5
  • Formula Weight
    363.95
  • Molecular Formula
    C20H26ClNOS
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 77.5 mg/mL (212.95 mM; Ultrasonic )H2O : 10 mg/mL (27.48 mM; Ultrasonic)
  • SMILES
    O.Cl.CN1CCCC(CC2c3ccccc3Sc3ccccc23)C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. J. Hagenah, et al. Exogenous levodopa is not toxic to elderly subjects with non-parkinsonian movement disorders: further clinical evidence. , 106(3-4), 301–307. doi:10.1007/s007020050159
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